All the guidance - in one* place
* - To make this navigable the list of guidance documents have been broken down into sub sectional pages - which I will make live over the next few weeks. Actually deciding how to order these is pretty challenging given the sheer variety of guidance out there.
Loosely the grouping of guidance areas is based on the standard chapter structure featured in Part 1 of EU/UK GMP Guidance as a starting point. To accommodate the areas that are usually scattered through the annexes I have altered this somewhat.
The chapters depart slightly from the common EU annex structure for convenience of grouping relevant guidance together.
If you think the guidance documents linked below are too thrilling you can also check our the primary legislation using our all the regulations in one place page.
1. Foundation Areas
Pharmaceutical Quality System
Personnel and Training
Premises, Utilities and Equipment
Data Integrity, Documentation and Computerised Systems
Qualification and Validation
QP Batch Certification and Release
Good Distribution Practise
Importation
2. GMP Activities - Preclinical and Clinical Development
Pharmaceutical Development and Quality by Design
CTD / PSF / Ethics
IMP Production and Manufacture
3. GMP Activities - Routine
Production and Manufacture
Quality Control and Testing
Auditing and Self inspection
Outsourced Activities
Complaints, Quality Defects and Product Recalls
Stability, Reference and Retention Samples
Sampling and Inspection
4. Product Type Specific Guidance
Active Substance and Excipients
Biological Active Substances and Medicinal Products
Sterility, Sterilisation and Sterility Assurance
Veterinary Medicinal Products
Medicinal Gases
Aerosols
Specials
Herbal medicines
If you think something is missing please contact me.
Disclaimer
This document is not a legal document not should it be interpreted in any fashion as a guide. This is a set of notes compiled as part of a personal CPD program. It is not complete or authoritative. I hope it gives you some value.
This is a personal effort and is not affiliated with my current role or employer.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. If you use it to train someone else, fantastic, but give the QP Notebook a plug. Thanks